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Reactions of Quino‐Ketenes with C‐Nucleophiles: Syntheses of (2‐Hydroxyphenyl)methanols and 2 ‐ Hydroxyphenyl Ketones
Author(s) -
Gündüz Hande,
Kumbaraci Volkan,
Talinli Naciye
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300391
Subject(s) - chemistry , nucleophile , catalysis , organic chemistry , reaction conditions , combinatorial chemistry
In this study, we have developed a new, efficient, and one‐step protocol for the synthesis of derivatives of 2,4‐dihydroxyphenyl ketones and/or 2,4‐dihydroxyphenyl/naphthalenyl methanols starting from benzodioxinones/naphthodioxinones and organolithium compounds. Reactions have been performed under thermal conditions without catalyst. This work is the first example of the preparation of these products starting from 2‐hydroxy acids.