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First Stereoselective and Concise Synthesis of Rhoiptelol C
Author(s) -
Purushotham Reddy Sudina,
Chinnababu Baggu,
Venkateswarlu Yenamandra
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300390
Subject(s) - chemistry , stereoselectivity , sharpless asymmetric dihydroxylation , dihydroxylation , stereochemistry , olefin fiber , total synthesis , enantioselective synthesis , metathesis , vanillin , combinatorial chemistry , organic chemistry , catalysis , polymer , polymerization
The first concise stereoselective total synthesis of diarylheptanoid rhoiptelol C ( 1 ) was achieved from readily available vanillin. The synthesis involves Keck 's asymmetric allylation, olefin cross metathesis, and Sharpless asymmetric dihydroxylation reaction as key steps.