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Reaction of Isonitriles with Dibenzoylacetylene Leading to Furan and Difuropyran Derivatives
Author(s) -
Adib Mehdi,
Feizi Shahzad,
Shahzad Shirazi Maryam,
Zhu LongGuan,
Reza Bijanzadeh Hamid
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300384
Subject(s) - chemistry , adduct , isocyanide , furan , medicinal chemistry , stereochemistry , organic chemistry
A mixture of an isocyanide and dibenzoylacetylene in dry CH 2 Cl 2 undergoes a smooth addition reaction at ambient temperature to furnish 3‐[5‐(alkylimino)‐3,4‐dibenzoyl‐2‐phenylfuran‐2(2 H )‐yl]‐ 1‐phenylprop‐2‐yn‐1‐ones (1 : 2 adduct) and {2,5‐bis(alkylimino)‐4,7,8a‐triphenyl‐5 H ‐difuro[2,3‐ b :3′,4′‐ e ]pyran‐3(8a H )‐yl}(phenyl)methanones (2 : 2 adduct). Single‐crystal X‐ray analyses conclusively confirmed the structures of the adducts.