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Chemical Constituents of the Endophytic Fungus Phomopsis sp. A240 Isolated from Taxus chinensis var. mairei
Author(s) -
Tao MeiHua,
Chen YuChan,
Wei XiaoYi,
Tan JianWen,
Zhang WeiMin
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300367
Subject(s) - phomopsis , chemistry , taxus , plant use of endophytic fungi in defense , bark (sound) , botany , sesquiterpene , terpene , fungus , stereochemistry , biology , ecology
A new sesquiterpene, eremophil‐9‐ene‐11,12,13‐triol ( 1 ), a new oxazole, 4‐(2‐hydroxyethyl)‐5‐methyloxazole ( 2 ), and the two known lactones, 5′‐hydroxyalternariol ( 3 ) and alternariol ( 4 ), were isolated from the extract of Phomopsis sp. A240, an endophytic fungus isolated from the bark of Taxus chinensis var. mairei. The structures of the isolated compounds were determined by analyses of their spectroscopic data, as well as by comparison with literature reports. The isolated compounds were evaluated for their cytotoxic and antioxidant activities.