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One‐Pot Synthesis of Pyrimido[1,2‐ a ]benzimidazoles under Solvent‐Free Conditions
Author(s) -
GhorbaniVaghei Ramin,
ToghraeiSemiromi Zahra,
KarimiNami Rahman,
Salimi Zahra
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300361
Subject(s) - chemistry , ethylbenzene , ethyl acetoacetate , catalysis , organic chemistry , solvent , simple (philosophy) , combinatorial chemistry , philosophy , epistemology
A series of pyrimido[1,2‐ a ]benzimidazoles were obtained from aldehydes, 2‐aminobenzimidazole and ethyl acetoacetate in good‐to‐excellent yields by a simple, mild, and efficient procedure utilizing N , N , N′ , N′ ‐tetrabromobenzene‐1,3‐disulfonamide (TBBDA) and poly( N ‐bromo‐ N ‐ethylbenzene‐1,3‐disulfonamide) (PBBS) as catalysts.
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