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Myrrhanolide D and Myrrhasin A, New Germacrane‐Type Sesquiterpenoids from the Resin of Commiphora opobalsamum
Author(s) -
Shen Tao,
Li GuoHui,
Zhong QingQing,
Wang ShuQi,
Ren DongMei,
Lou HongXiang,
Wang XiaoNing
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300328
Subject(s) - chemistry , du145 , stereochemistry , organic chemistry , prostate cancer , cancer , medicine , lncap
Two new germacrane‐type sesquiterpenoids bearing an epoxy ring, myrrhanolide D ( 1 ) and myrrhasin A ( 2 ), together with eight known compounds, 3 – 10 , were isolated from the resinous exudates of Commiphora opobalsamum. Their structures were elucidated based on the analyses of their spectroscopic data. The isolated compounds 1, 2, 6 , and 8 were evaluated for their cytotoxic activities against human prostate cancer DU145 and PC3 cells.