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Further Diterpenes from the Seeds of Caesalpinia minax Hance
Author(s) -
Ma GuoXu,
Wu HaiFeng,
Yuan JingQuan,
Wei Hua,
Wang Shuo,
Zhang XiaoPo,
Tian Yu,
Yang JunShan,
Xu XuDong
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300220
Subject(s) - chemistry , diterpene , caesalpinia , stereochemistry , terpene , cancer cell lines , bark (sound) , traditional medicine , cancer cell , cancer , biology , medicine , genetics , ecology
Three new cassane‐type diterpenes, neocaesalpin AF ( 1 ), neocaesalpin AG ( 2 ), and neocaesalpin AH ( 3 ), were isolated from the seeds of Caesalpinia minax Hance . Their structures were elucidated on the basis of extensive spectroscopic analyses. The partially hydrogenated lactone unit in a tetracyclic cassane diterpene in 2 is rarely encountered in the cassane diterpenes isolated from the genus Caesalpinia. All compounds were evaluated for their in vitro cytotoxic activities against HCT‐8 and MCF‐7 human cancer cell lines.