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Two New Phenolic Compounds from Artemisia iwayomogi
Author(s) -
Yan XiTao,
Ding Yan,
Li Wei,
Sun YaNan,
Yang SeoYoung,
Koh YoungSang,
Kim YoungHo
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300170
Subject(s) - chemistry , artemisia , quercetin , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , glucuronide , organic chemistry , biochemistry , traditional medicine , metabolism , medicine , antioxidant
Two new phenolic compounds, ( Z )‐5′‐hydroxyjasmone 5′‐ O ‐{6″‐ O ‐[( E )‐caffeoyl]‐ β ‐ D ‐glucopyranoside} ( 1 ) and quercetin‐7‐ O ‐ β ‐ D ‐glucuronide methyl ester ( 2 ), along with ten known phenolic compounds, 3 – 12 , were isolated from the aerial parts of Artemisia iwayomogi. Their structures were elucidated by spectroscopic methods, including 1D‐ and 2D‐NMR, and HR‐ESI‐TOF‐MS techniques. The inhibitory effects of compounds 1 – 12 on the LPS‐stimulated production of IL‐12 p40, IL‐6, and TNF‐ α in bone marrow‐derived dendritic cells were evaluated.