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Two Novel Abietane Diterpenoids from Illicium wardii A.C. Sm .
Author(s) -
Gao YanPing,
Shen YunHeng,
Zhang WeiDong
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300160
Subject(s) - abietane , chemistry , terpenoid , stereochemistry , diterpene , two dimensional nuclear magnetic resonance spectroscopy , terpene , nuclear magnetic resonance spectroscopy
Two novel abietane diterpenoids, wardinols A and B ( 1 and 2 , resp.), together with five known diterpenoids, 3 – 7 , were isolated from the fruits of Illicium wardii A.C. Sm . Their structures were elucidated on the basis of intensive spectroscopic analysis, including 1D‐ and 2D‐NMR spectroscopy. Wardinol A ( 1 ) is a rare 9,10‐epoxy‐9,10‐secoabietane diterpenoid. All of the isolated compounds were evaluated for their cytotoxicities against three human tumor cell lines, A549, HCT116, and CCRF‐CEM.