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Two New Indole Alkaloids from Emmenopterys henryi
Author(s) -
Wu XingDe,
Wang Lei,
He Juan,
Li XingYao,
Dong LiaoBin,
Gong Xun,
Gao Xiu,
Song LiuDong,
Li Yan,
Peng LiYan,
Zhao QinShi
Publication year - 2013
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300050
Subject(s) - indole test , chemistry , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , alkaloid
Two new indole alkaloids, 5‐oxodolichantoside ( 1 ) and deglycocadambine ( 2 ), were isolated from the twigs and leaves of Emmenopterys henryi , together with four known indole alkaloids and five known iridoids. The structures of the new compounds were elucidated on the basis of extensive spectroscopic analyses, including 1D‐ and 2D‐NMR experiments, and confirmed by single‐crystal X‐ray diffraction studies. This is the first report on the isolation of indole alkaloids from this species. The indole alkaloids were evaluated for their cytotoxic activities against five human cancer lines.