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Three New Triterpene Saponins from Bolbostemma paniculatum
Author(s) -
Tang Yun,
Cao JiaQing,
Li Wei,
Li Wei,
Zhao YuQing
Publication year - 2014
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201300008
Subject(s) - triterpene , chemistry , dammarane , saponin , stereochemistry , terpene , ranunculaceae , two dimensional nuclear magnetic resonance spectroscopy , traditional medicine , botany , biology , medicine , alternative medicine , pathology
Two novel noroleanane saponins, tubeimoside A ( 1 ) and tubeimoside B ( 2 ), and a new dammarane triterpene saponin, tubeimoside C ( 3 ), together with two known compounds, 4 and 5 , were isolated from the bulbs of Bolbostemma paniculatum ( Maxim .) Franquet . Compound 4 was found in this genus for the first time. Based on spectroscopic methods, including IR, NMR (DEPT, COSY, HMQC, HMBC, and TOCSY), and MS experiments, and chemical reactions, the structures of the new compounds were elucidated as 3 β ‐[ β ‐ D ‐glucopyranosyl‐(1→2)‐ β ‐ D ‐glucopyranosyloxy]‐2 β ,23‐dihydroxy‐28‐norolean‐12‐en‐16‐one ( 1 ), 3 β ‐[ β ‐ D ‐glucopyranosyl‐(1→2)‐ β ‐ D ‐glucopyranosyloxy]‐2 β ,23‐dihydroxy‐28‐norolean‐12‐en‐22‐one ( 2 ), (3 β ,7 β )‐7,18,20‐trihydroxydammar‐24‐en‐3‐yl 2‐ O ‐ α ‐ L ‐arabinopyranosyl‐ β ‐ D ‐glucopyranoside ( 3 ).