Biotransformation of Jervine by Cunninghamella echinulata

Biotransformation of jervine ( 1 ) by Cunninghamella echinulata (ACCC 30369) was carried out. Four biotransformation products were obtained, and three of them, 3 – 5 , were identified as new compounds. On the basis of their NMR and mass‐spectral data, their structures were characterized as jervinone ( 2 ), 7 α ‐hydroxyjervine ( 3 ), 14 α ‐hydroxyjervine ( 4 ), and 1 β ,7 α ‐dihydroxyjervine ( 5 ). The X‐ray diffraction structure of 1 is also reported for the first time.