Premium
Triterpenoids from the Roots of Camellia oleifera C. Abel and Their Cytotoxic Activities
Author(s) -
Wang ShouLi,
Chen Zhong,
Tong XiaoJing,
Liu YanLi,
Li Xia,
Xu QiongMing,
Li XiaoRan,
Yang ShiLin
Publication year - 2013
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201200333
Subject(s) - chemistry , camellia oleifera , triterpenoid , stereochemistry , cytotoxic t cell , bromide , traditional medicine , organic chemistry , biochemistry , in vitro , medicine
Three new triterpenoids, 21 β ,22 α ‐diangeloyloxy‐3 β ,15 α ,16 α ,28‐tetrahydroxyolean‐12‐en‐23‐al ( 1 ), 21 β ‐angeloyloxy‐3 β ,15 α ,16 α ,28‐tetrahydroxy‐22 α ‐(2‐methylbutanoyloxy)olean‐12‐en‐23‐al ( 2 ), and 21 β ‐angeloyloxy‐3 β ,16 α ,28‐trihydroxy‐22 α ‐(2‐methylbutanoyloxy)olean‐12‐en‐23‐al ( 3 ), along with six known triterpenoids, were isolated from the roots of Camellia oleifera C. Abel . The structures of compounds 1 – 3 were elucidated on the basis of spectroscopic analyses. Moreover, all compounds isolated were evaluated for their cytotoxic activities by MTT (=3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl‐2 H ‐tetrazolium bromide) assay.