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Ergostane Steroids from Dysoxylum lukii
Author(s) -
Hu Jiang,
Song Yan,
Shi XiaoDong,
Mao Xia,
Chen JianGang,
Zhu Lei
Publication year - 2013
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201200207
Subject(s) - chemistry , two dimensional nuclear magnetic resonance spectroscopy , triol , stereochemistry , phytochemical , bark (sound) , organic chemistry , diol , biochemistry , physics , acoustics
Phytochemical investigation of the 70% EtOH extract from the stem bark of Dysoxylum lukii led to the isolation of three new ergostane steroids, (3 β )‐3,20‐dihydroxyergosta‐5,24(28)‐dien‐7‐one ( 1 ), (3 β ,4 β ,7 α )‐ergosta‐5,24(28)‐diene‐3,4,7‐triol ( 2 ), and (3 β ,7 α )‐3,20‐dihydroxyergosta‐5,24(28)‐dien‐7‐yl acetate ( 3 ), together with the known compound (3 β ,4 β )‐ergosta‐5,24(28)‐diene‐3,4,20‐triol ( 4 ). Their structures were elucidated on the basis of extensive 1D‐ and 2D‐NMR (COSY, HMQC, HMBC, and NOESY) analyses.