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A New Glycine Derivative and a New Indole Alkaloid from the Fermentation Broth of the Plant Endophytic Fungus Pestalotiopsis podocarpi Isolated from the Chinese Podocarpaceae Plant Podocarpus macrophyllus
Author(s) -
Luo DuQiang,
Chen YuPeng,
Zhang Jun,
Shi BaoZhong,
Yang ZiQi,
Chen Chuan
Publication year - 2013
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201200166
Subject(s) - chemistry , indole alkaloid , stereochemistry , derivative (finance) , alkaloid , indole test , carbamic acid , organic chemistry , financial economics , economics
A new glycine derivative, podocarpiamide ( 1 ), a new indole alkaloid, 1‐methoxy‐1 H ‐indol‐3‐ethanol ( 2 ), together with two known compounds, 1‐methoxy‐1 H ‐indole‐3‐acetic acid ( 3 ) and methyl 1‐methoxy‐1 H ‐indole‐3‐acetate ( 4 ), were isolated from the fermentation broth of the plant endophytic fungus Pestalotiopsis podocarpi. Their structures were elucidated by extensive spectroscopic analysis including 1D‐ and 2D‐NMR (HSQC, HMBC, and COSY) and MS experiments. Compound 1 has an interesting unusual carbamic acid structure.