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Synthesis of Thienyl‐Substituted Dihydrofuran Compounds Promoted by Manganese(III) Acetate
Author(s) -
Biçer Emre,
Yılmaz Mehmet,
Burgaz E. Vildan,
Pekel A. Tarık
Publication year - 2013
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201200098
Subject(s) - chemistry , manganese(iii) acetate , substituent , manganese , carbocation , medicinal chemistry , organic chemistry
Radical cyclization reactions of both aliphatic 1,3‐diones 1a and 1b and of cyclic 1,3‐diones 1c – 1e with 2‐thienyl‐ and 3‐thienyl‐substituted alkenes 2a – 2d in the presence of manganese(III) acetate were investigated. Thienyl‐substituted dihydrofurans 3 were obtained with moderate to high yields ( Table 1 – 3 ). Also, the favorable effect of the thienyl substituent on the intermediate carbocation stability was evaluated by comparison with a phenyl substituent.