Premium
Six New Sesquiterpenes from Eupatorium lindleyanum
Author(s) -
Wu ShuangQing,
Xu NaiYu,
Sun Qun,
Han HaiYan,
Zhang Jian
Publication year - 2012
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201200083
Subject(s) - chemistry , cytotoxicity , stereochemistry , eupatorium , k562 cells , two dimensional nuclear magnetic resonance spectroscopy , in vitro , traditional medicine , biochemistry , medicine
The six new germacrane‐type sesquiterpenoid lactones 1 – 6 were isolated from the CHCl 3 extract of Eupatorium lindleyanum DC. The structures of these compounds were determined by spectroscopic analyses, including interpretation of 1D‐ and 2D‐NMR spectra. Compounds 1 – 6 were tested for cytotoxicity against NB4 and K562 leukemia cell lines, showing that 2 and 5 possess potent cytotoxicity ( Table 3 ).