Premium
Two New Triterpene Saponins from Cyclamen africanum Boiss . & Reuter
Author(s) -
BencharifBetina Soumeya,
Miyamoto Tomofumi,
Tanaka Chiaki,
Kabouche Zahia,
MitaineOffer AnneClaire,
LacailleDubois Marie Aleth
Publication year - 2012
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201200041
Subject(s) - chemistry , triterpene , stereochemistry , triterpenoid , oleanane , saponin , two dimensional nuclear magnetic resonance spectroscopy , terpene , medicine , alternative medicine , pathology
Two new oleanane‐type triterpene saponins, afrocyclamins A and B ( 1 and 2 , resp.), were isolated from a MeOH extract of the roots of Cyclamen africanum Boiss . & Reuter , together with three known triterpenoid saponins, lysikokianoside, deglucocyclamin I, and its dicrotalic acid derivative. The structures were elucidated, on the basis of 1D‐ and 2D‐NMR experiments and mass spectrometry as (3 β ,20 β )‐13,28‐epoxy‐16‐oxo‐3‐{ O ‐ β ‐ D ‐xylopyranosyl‐(1→2)‐ O ‐ β ‐ D ‐glucopyranosyl‐(1→4)‐ O ‐[ β ‐ D ‐glucopyranosyl‐(1→2)]‐ α ‐ L ‐arabinopyranosyl}oxy}oleanan‐29‐al ( 1 ) and (3 β ,16 α ,20 β )‐16,28,29‐trihydroxy‐olean‐12‐en‐3‐yl O ‐4‐ O ‐(4‐carboxy‐3‐hydroxy‐3‐methyl‐1‐oxobutyl)‐ β ‐ D ‐xylopyranosyl‐(1→2)‐ O ‐ β ‐ D ‐glucopyranosyl‐(1→4)‐ O ‐[ β ‐ D ‐glucopyranosyl‐(1→2)]‐ α ‐ L ‐arabinopyranoside ( 2 ).