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MizorokiHeck and Sonogashira Cross‐Couplings Catalyzed by CNC Palladium Pincer Complexes in Organic and Aqueous Media
Author(s) -
SanMartin Raul,
Inés Blanca,
Moure María Jesús,
Herrero María Teresa,
Domínguez Esther
Publication year - 2012
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100503
Subject(s) - sonogashira coupling , pincer movement , chemistry , catalysis , palladium , aqueous medium , aqueous solution , polymer chemistry , combinatorial chemistry , organic chemistry , medicinal chemistry
The catalytic activity of two CNC palladium pincer complexes is evaluated in two fundamental CC bond‐forming reactions: MizorokiHeck and Sonogashira cross‐couplings. After several optimization attempts and a brief comparison with a PCN pincer catalyst, a number of arylated alkenes and diarylethynes are synthesized by procedures based on the catalytic use of the above mentioned CNC Pd pincers in H 2 O and DMF.