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X‐Ray Structure Study of an Unusual 13,14,15,16‐Tetranorlabdane Derivative Obtained in the Synthesis of (7 α )‐7,8‐Dihydroxy‐14,15‐dinorlabdane‐11,13‐dione
Author(s) -
Kravtsov Victor C.,
Gorincioi Elena C.,
Barba Alic N.,
Aricu Aculi.,
Lipkowski Janusz,
Vlad Pavel F.
Publication year - 2012
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100412
Subject(s) - chemistry , derivative (finance) , crystal structure , x ray , hydrolysis , stereochemistry , crystallography , organic chemistry , physics , quantum mechanics , financial economics , economics
The unconventional (5 S ,7 R ,8 S ,9 R ,10 S )‐configurated (−)‐7‐(acetyloxy)‐12,12‐dichloro‐8‐hydroxy‐13,14,15,16‐tetranorlabdan‐11‐one ( 2 ) was synthesized via the HCl‐promoted hydrolysis of (7 α )‐7,8‐(isopropylidenedioxy)‐14,15‐dinorlabdan‐11,13‐dione ( 5 ). Possible mechanistic pathways of the reaction are considered. Crystal and molecular structures of the isolated compound 2 were determined by single‐crystal X‐ray structure analysis.