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An Efficient One‐Pot Synthesis of Substituted 1 H ‐Naphtho[2,1‐ b ]pyrans and 4 H ‐1‐Benzopyrans (=Chromenes) under Solvent‐Free Microwave‐Irradiation Conditions
Author(s) -
Shekhar Adimulam Chandra,
Kumar Akula Ravi,
Sathaiah Gangaram,
Raju Kengiri,
Rao Pamulaparthy Shanthan,
Sridhar Madabhushi,
Narsaiah Banda,
Srinivas Punnamraju Venkata Satya Surya,
Sridhar Balasubramanian
Publication year - 2012
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100332
Subject(s) - chemistry , benzopyrans , methylene , microwave irradiation , pyran , phenol , aldehyde , solvent , aryl , benzopyran , catalysis , organic chemistry , medicinal chemistry , alkyl
A facile heterogeneous synthesis of 3‐amino‐1‐aryl‐1 H ‐naphtho[2,1‐ b ]pyran and 2‐amino‐4‐aryl‐4 H ‐1‐benzopyran derivatives 3 and 5 , respectively, was carried out efficiently by one‐pot three‐component coupling of an aromatic aldehyde 1 , an active methylene compound 2 , and naphthalen‐2‐ol or a phenol 4 in the presence of 5‐Å molecular sieves under solvent‐free microwave‐irradiation conditions ( Scheme 1 and 2, Tables 1 and 2 ). The catalyst was recovered and recycled ( Table 3 ).