Premium
Two New Sesquiterpenes from the Marine Fungus Eutypella scoparia FS26 from the South China Sea
Author(s) -
Sun Li,
Li DongLi,
Tao MeiHua,
Dan FeiJun,
Zhang WeiMin
Publication year - 2012
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100275
Subject(s) - sesquiterpene , terpene , chemistry , scoparia , hydroxymethyl , stereochemistry , fungus , botany , biology
A new monocyclofarnesane‐type sesquiterpene, 3,7,10‐trihydroxy‐6,11‐cyclofarnes‐1‐ene ( 1 ), and a new acorane‐type sesquiterpene, 8‐(hydroxymethyl)‐1‐(2‐hydroxy‐1‐methylethyl)‐4‐methylspiro[4.5]dec‐8‐en‐7‐ol ( 2 ), were isolated from the culture of Eutypella scoparia FS26 from the South China Sea, along with three known terpenes, 3 – 5 . The structures of these compounds were determined by extensive analysis of their spectroscopic data as well as by comparison with literature reports. The isolated compounds 1 – 5 were evaluated for their cytotoxic activities against the SF‐268, MCF‐7, and NCI‐H460 tumor cell lines.