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Aluminium Nitrate Nonahydrate (Al(NO 3 ) 3 ⋅9 H 2 O): An Efficient Oxidant Catalyst for the One‐Pot Synthesis of Biginelli Compounds from Benzyl Alcohols
Author(s) -
Kolvari Eskandar,
Zolfigol Mohammad Ali,
Mirzaeean Maryam
Publication year - 2012
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100242
Subject(s) - chemistry , thiourea , catalysis , biginelli reaction , urea , aryl , organic chemistry , primary (astronomy) , one pot synthesis , oxidative phosphorylation , medicinal chemistry , biochemistry , alkyl , physics , astronomy
A clean and efficient tandem oxidative cyclocondensation process is reported for the synthesis of 3,4‐dihydropyrimidin‐2(1 H )‐one or ‐thione derivatives from primary aryl alcohols, β ‐keto esters, and urea or thiourea in the presence of Al(NO 3 ) 3 ⋅9 H 2 O as oxidant catalyst ( Scheme, Table 5 ).