Premium
Diastereoisomeric ent ‐Labdane Diterpenoids from Andrographis paniculata
Author(s) -
Hu YongMei,
Wang GuoCai,
Wang Ying,
Sung Herman H.Y.,
Williams Ian D.,
Ye WenCai
Publication year - 2012
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100236
Subject(s) - labdane , andrographis paniculata , chemistry , diastereomer , andrographolide , stereochemistry , acanthaceae , diterpene , traditional medicine , organic chemistry , medicine , alternative medicine , pathology
Four C(8),C(12)‐diastereoisomers, (8 S ,12 S )‐isoandrographolide ( 1 ), (8 S ,12 R )‐isoandrographolide ( 2 ), (8 R ,12 R )‐isoandrographolide ( 3 ), and (8 R ,12 S )‐isoandrographolide ( 4 ) were isolated from the aerial parts of Andrographis paniculata. The structures of the new compounds 1 – 3 were established on the basis of the spectroscopic data including UV, IR, NMR, HR‐ESI‐MS, and X‐ray diffraction analysis.