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Two New Cytotoxic Alkaloids from Mappianthus iodoides Hand.‐Mazz.
Author(s) -
Xiao XiBin,
Lin YueXing,
Xu GengBo,
Gong XuBo,
Gu Ying,
Tong JieFeng,
Yang Jing
Publication year - 2011
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100187
Subject(s) - chemistry , cytotoxic t cell , stereochemistry , nuclear magnetic resonance spectroscopy , two dimensional nuclear magnetic resonance spectroscopy , mass spectrometry , biochemistry , chromatography , in vitro
Two new alkaloids, mappine A ( 1 ) and mapposidic acid ( 2 ), together with eleven known compounds, were isolated from the stems of Mappianthus iodoides Hand.‐Mazz. Their structures were elucidated by means of spectroscopic and mass‐spectrometric analyses, particularly 1D‐ and 2D‐NMR spectroscopy. The cytotoxic activities of the two new alkaloids were also evaluated.