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Two New Cryptoporic Acid Derivatives from the Fruiting Bodies of Cryptoporus sinensis
Author(s) -
Wu Wen,
Zhao Feng,
Bao Li,
Lu JinCai,
Liu HongWei
Publication year - 2011
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100100
Subject(s) - chemistry , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , cytotoxic t cell , biochemistry , in vitro
Two new drimane‐type sesquiterpenoid ethers of isocitric acid, cryptoporic acids N ( 1 ) and O ( 6 ), were isolated from the fruiting bodies of Cryptoporus sinensis. Their structures were established by means of spectroscopic methods, including 1D‐ and 2D‐NMR. The cytotoxic activity against a panel of cell lines (A549, MCF‐7, PC‐3, and PANC‐1) was evaluated for all cryptoporic acid derivatives 1 – 12 isolated.