A Convenient Synthesis of Functionalized  α ‐Methylidenebutano‐4‐lactams | Zendy

Liberge Gwenaëlle | Zendy; Lebrun Stéphane | Zendy; Couture Axel | Zendy; Grandclaudon Pierre | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A Convenient Synthesis of Functionalized α ‐Methylidenebutano‐4‐lactams

Author(s) -

Liberge Gwenaëlle,

Lebrun Stéphane,

Couture Axel,

Grandclaudon Pierre

Publication year - 2011

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.201100070

Subject(s) - chemistry , metalation , alkylation , lactam , combinatorial chemistry , sequence (biology) , elaboration , stereochemistry , organic chemistry , catalysis , biochemistry , philosophy , humanities

A concise synthetic approach to functionalized α ‐methylidenebutanolactams has been developed. The synthetic strategy is based on the preliminary assembly of the lactam template equipped with appropriate functionalities. Subsequent installation of the methylidene by a metalation/alkylation/elimination sequence completed the elaboration of the racemic title compounds.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research