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A Simple One‐Pot Synthesis of N ‐Alkyl‐2,5‐diaryl‐1,3‐dioxol‐4‐amines
Author(s) -
Bayat Mohammad,
Nasri Shima
Publication year - 2011
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100052
Subject(s) - chemistry , alkyl , one pot synthesis , simple (philosophy) , organic chemistry , medicinal chemistry , combinatorial chemistry , catalysis , philosophy , epistemology
An efficient procedure for the synthesis of N ‐alkyl‐2,5‐diaryl‐1,3‐dioxol‐4‐amines 3 via a one‐pot reaction of aromatic aldehydes 2 and alkyl isocyanides 1 at room temperature in good yields is described ( Scheme 1, Table ).