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A New Four‐Component Reaction for the Synthesis of Spiro[4 H ‐indeno[1,2‐ b ]pyridine‐4,3′‐[3 H ]indoles]
Author(s) -
Feiz Afsaneh,
Shakibaei Ghazaleh Imani,
Yasaei Zahra,
Reza Khavasi Hamid,
Bazgir Ayoob
Publication year - 2011
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100047
Subject(s) - chemistry , acenaphthylene , pyridine , indane , indole test , catalysis , toluene , medicinal chemistry , component (thermodynamics) , isatin , organic chemistry , stereochemistry , naphthalene , physics , thermodynamics
A new four‐component synthesis of spiro[4 H ‐indeno[1,2‐ b ]pyridine‐4,3′‐[3 H ]indoles] and spiro[acenaphthylene‐1(2 H ),4′‐[4 H ‐indeno[1,2‐ b ]pyridines] by the reaction of indane‐1,3‐dione, 1,3‐dicarbonyl compounds, isatins (=1 H ‐indole‐2,3‐diones) or acenaphthylene‐1,2‐dione, and AcONH 4 in refluxing toluene in the presence of a catalytic amount of pyridine is reported.