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Xestospongienols A–L, Brominated Acetylenic Acids from the Chinese Marine Sponge Xestospongia testudinaria
Author(s) -
Liu Dong,
Xu Jing,
Jiang Wei,
Deng Zhiwei,
de Voogd Nicole J.,
Proksch Peter,
Lin Wenhan
Publication year - 2011
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201100015
Subject(s) - chemistry , sponge , polyene , stereochemistry , acetylene , alkyl , organic chemistry , botany , biology
Chemical examination of the Chinese marine sponge Xestospongia testudinaria resulted in the isolation and characterization of twelve new brominated acetylenic acids, namely xestospongienols A–L ( 1a – 1d, 2a – 2d , and 3a – 3d ), together with the known analog 4 . The structures of xestospongienols A–L were determined on the basis of 1D‐ and 2D‐NMR, IR, and MS analysis in association with the modified Mosher method. The structural patterns are characteristic of brominated unbranched C 16 ‐alkyl chains containing polyene and acetylene moieties.