Highly Enantioselective Synthesis of Orthogonally Protected (2 S )‐2,3‐Diaminopropanoates through Catalytic Phase‐Transfer Aza‐ Henry  Reaction | Zendy

Kumaraswamy Gullapalli | Zendy; Pitchaiah Arigala | Zendy

Premium

Highly Enantioselective Synthesis of Orthogonally Protected (2 S )‐2,3‐Diaminopropanoates through Catalytic Phase‐Transfer Aza‐ Henry Reaction

Author(s) -

Kumaraswamy Gullapalli,

Pitchaiah Arigala

Publication year - 2011

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.201100013

Subject(s) - chemistry , enantioselective synthesis , organocatalysis , enantiomer , chirality (physics) , catalysis , stereochemistry , combinatorial chemistry , organic chemistry , nambu–jona lasinio model , chiral symmetry breaking , physics , quantum mechanics , quark

The syntheses of enantiomer‐enriched orthogonally protected different (2 S )‐2,3‐diaminopropanoates and unnatural furyl‐substituted ( tert ‐butoxy)carbonyl (Boc) as well as (benzyloxy)carbonyl (Cbz) protected amino acid esters are accomplished by means of an enantioselective aza‐ Henry reaction. A key feature of this protocol is organocatalysis as a genesis of chirality to ensure high enantioselectivity.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research