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Meliarachins A–K: Eleven Limonoids from the Twigs and Leaves of Melia azedarach
Author(s) -
Su ZuShang,
Yang ShengPing,
Zhang Sheng,
Dong Lei,
Yue JianMin
Publication year - 2011
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201000444
Subject(s) - melia azedarach , chemistry , meliaceae , limonoid , traditional medicine , botany , antibacterial activity , stereochemistry , bacteria , biology , medicine , genetics
Eleven new limonoids, meliarachins A–K ( 1 – 11 , resp.), together with five known ones, were isolated from the twigs and leaves of Melia azedarach. The structures of the new compounds were elucidated on the basis of spectroscopic analysis. Compounds 4 and 8 exhibited moderate antibacterial activities against Gram ‐positive bacteria.