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Two New Steroidal Saponins from the Fresh Leaves of Agave sisalana
Author(s) -
Yu HeShui,
Zou Peng,
Song XinBo,
Kang LiPing,
Liu YiXun,
Pang Xu,
Zhang Jie,
Fu Jing,
Zhao Yang,
Xiong ChengQi,
Tan DaWei,
Zhang LiJuan,
Ma BaiPing
Publication year - 2011
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201000442
Subject(s) - agave , saponin , chemistry , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , botany , medicine , alternative medicine , pathology , biology
A new furostanol saponin, sisalasaponin C ( 1 ), and a new spirostanol saponin, sisalasaponin D ( 2 ), were isolated from the fresh leaves of Agave sisalana , along with three other known steroidal saponins and two stilbenes. Their structures were identified as (3 β ,5 α ,6 α ,22 α ,25 R )‐3,26‐bis[( β ‐ D ‐glucopyrano‐ syl)oxy]‐22‐hydroxyfurostan‐6‐yl β ‐ D ‐glucopyranoside ( 1 ), (3 β ,5 α ,25 R )‐12‐oxospirostan‐3‐yl 6‐deoxy‐ α ‐ L ‐mannopyranosyl‐(1→4)‐ β ‐ D ‐glucopyranosyl‐(1→3)‐[ β ‐ D ‐xylopyranosyl‐(1→3)‐ β ‐ D ‐glucopyranosyl‐(1→2)]‐ β ‐ D ‐glucopyranosyl‐(1→4)‐ β ‐ D ‐galactopyranoside ( 2 ), (3 β ,5 α ,6 α ,22 α ,25 R )‐22‐methoxyfurostane‐3,6,26‐triyl tris‐ β ‐ D ‐glucopyranoside, cantalasaponin‐1, polianthoside D, ( E )‐ and ( Z )‐2,3,4′,5‐tetrahydroxystilbene 2‐ O‐β ‐ D ‐glucopyranosides. The last three known compounds were isolated from the fresh leaves of Agavaceae for the first time. The structures of the new compounds were elucidated by detailed spectroscopic analysis, including 1D‐ and 2D‐NMR experiments, and chemical techniques.