Indium(III) Chloride‐Catalyzed Conversion of {[(Benzyloxy)carbonyl]amino}‐Substituted Sulfones with 2‐[(Trimethylsilyl)oxy]furan: A Facile Access to  γ ‐Butenolactone Derivatives Containing a Protected Amino Group | Zendy

Das Biswanath | Zendy; Sudhakar Chithaluri | Zendy; Reddy Parigi Raghavendar | Zendy; Kashanna Jajula | Zendy

Premium

Indium(III) Chloride‐Catalyzed Conversion of {[(Benzyloxy)carbonyl]amino}‐Substituted Sulfones with 2‐[(Trimethylsilyl)oxy]furan: A Facile Access to γ ‐Butenolactone Derivatives Containing a Protected Amino Group

Author(s) -

Das Biswanath,

Sudhakar Chithaluri,

Reddy Parigi Raghavendar,

Kashanna Jajula

Publication year - 2011

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.201000366

Subject(s) - chemistry , trimethylsilyl , furan , catalysis , indium , medicinal chemistry , trimethylsilyl chloride , carbonyl group , chloride , organic chemistry , group (periodic table)

Treatment of {[(benzyloxy)carbonyl]amino}‐substituted sulfones 1 with 2‐[(trimethylsilyl)oxy]furan ( 2 ) in the presence of InCl 3 as a catalyst at room temperature produced the γ ‐butenolactone derivatives 3 and 4 containing a protected amino group ( Scheme 1 ). The products were formed in high yields (81–92%) within 3–10 h favoring the anti ‐isomer 3 .

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research