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Two New Abietane Diterpenoids from the Stems of Clerodendrum kaichianum P. S. Hsu
Author(s) -
Xu Mingfeng,
Shen Lianqing,
Wang Kuiwu,
Du Qizhen
Publication year - 2011
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201000312
Subject(s) - abietane , chemistry , diterpene , stereochemistry , terpene , terpenoid
Abstract Two new abietane diterpenoids, named 17‐hydroxyteuvincenone G ( 1 ) and 17‐hydroxyteuvincen‐5(6)‐enone G ( 2 ), together with four known diterpenoids, were isolated from the stems of Clerodendrum kaichianum P. S. Hsu . Their structures were elucidated by extensive NMR and MS analyses, and by comparison with literature data. The new compounds showed significant cytotoxicities against the HL‐60 and A‐549 tumor cell lines.