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Three New Triterpenoid Saponins from Ardisia crenata
Author(s) -
Liu DaiLin,
Wang NaiLi,
Zhang Xue,
Yao XinSheng
Publication year - 2011
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201000285
Subject(s) - chemistry , triterpenoid , stereochemistry , triterpenoid saponin , saponin , spectral analysis , spectroscopy , medicine , physics , alternative medicine , pathology , quantum mechanics
Three new triterpenoid saponins, ardisicrenoside I ( 1 ), ardisicrenoside J ( 2 ), and ardisicrenoside M ( 3 ), along with eight known compounds, were isolated from the roots of Ardisia crenata Sims . Their structures were elucidated as 16 α ‐hydroxy‐30,30‐dimethoxy‐3 β ‐ O ‐{ β ‐ D ‐xylopyranosyl‐(1→2)‐ β ‐ D ‐glucopyranosyl‐(1→4)‐[ β ‐ D ‐glucopyranosyl‐(1→2)]‐ α ‐ L ‐arabinopyranosyl}‐13 β ,28‐epoxyoleanane ( 1 ), 16 α ‐hydroxy‐30,30‐dimethoxy‐3 β ‐ O ‐{ α ‐ L ‐rhamnopyranosyl‐(1→2)‐ β ‐ D ‐glucopyranosyl‐(1→4)‐[ β ‐ D ‐glucopyranosyl‐(1→2)]‐ α ‐ L ‐arabinopyranosyl}‐13 β ,28‐epoxyoleanane ( 2 ), 30,30‐dimethoxy‐16‐oxo‐3 β ‐ O ‐{ β ‐ D ‐xylopyranosyl‐(1→2)‐ β ‐ D ‐glucopyranosyl‐(1→4)‐[ β ‐ D ‐glucopyranosyl‐(1→2)]‐ α ‐ L ‐arabinopyranosyl}‐13 β ,28‐epoxyoleanane ( 3 ), ardisiacrispin A ( 4 ), ardisiacrispin B ( 5 ), ardisicrenoside B ( 6 ), ardisicrenoside A ( 7 ), ardisicrenoside H ( 8 ), ardisicrenoside G ( 9 ), cyclamiretin A‐3 β ‐ O ‐ β ‐ D ‐xylopyranosyl‐(1→2)‐ β ‐ D ‐glucopyranosyl‐(1→4)‐ α ‐ L ‐arabinopyranoside ( 10 ), and cyclamiretin A‐3 β ‐ O ‐ α ‐ L ‐rhamnopyranosyl‐(1→2)‐ β ‐ D ‐glucopyranosyl‐(1→4)‐ α ‐ L ‐arabinopyranoside ( 11 ) by means of chemical and spectral analysis, and their cytotoxicities were evaluated in vitro.