An Efficient Synthesis of [(Tosylamino)alkyl]naphthalenols by Nucleophilic Addition of Naphthalen‐2‐ol with  N ‐Tosyl Imines Using Boron Trifluoride Etherate as Catalyst | Zendy

Das Biswanath | Zendy; Reddy Cheruku Ravindra | Zendy; Sindhu Chava | Zendy; Kumar Duddukuri Nandan | Zendy; Krishnaiah Martha | Zendy

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An Efficient Synthesis of [(Tosylamino)alkyl]naphthalenols by Nucleophilic Addition of Naphthalen‐2‐ol with N ‐Tosyl Imines Using Boron Trifluoride Etherate as Catalyst

Author(s) -

Das Biswanath,

Reddy Cheruku Ravindra,

Sindhu Chava,

Kumar Duddukuri Nandan,

Krishnaiah Martha

Publication year - 2011

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.201000224

Subject(s) - chemistry , boron trifluoride , tosyl , nucleophile , catalysis , alkyl , medicinal chemistry , nucleophilic addition , boron , organic chemistry

[(Tosylamino)alkyl]naphthalenols have efficiently been synthesized by nucleophilic addition of naphthalen‐2‐ol with N‐ tosyl imines (derived from both aromatic and aliphatic aldehydes) in the presence of BF 3 ⋅OEt 2 as a catalyst at room temperature. The products are formed within 5–9 h in high yields (72–91%).

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