The Reaction of ( N ‐Isocyanimino)triphenylphosphorane with Biacetyl in the Presence of Aromatic Carboxylic Acids: Efficient One‐Pot Three‐Component Reaction for the Synthesis of 3‐(5‐Aryl‐1,3,4‐oxadiazol‐2‐yl)‐3‐hydroxybutan‐2‐one Derivatives | Zendy

Ramazani Ali | Zendy; Rouhani Morteza | Zendy; Rezaei Aram | Zendy; Shajari Nahid | Zendy; Souldozi Ali | Zendy

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The Reaction of ( N ‐Isocyanimino)triphenylphosphorane with Biacetyl in the Presence of Aromatic Carboxylic Acids: Efficient One‐Pot Three‐Component Reaction for the Synthesis of 3‐(5‐Aryl‐1,3,4‐oxadiazol‐2‐yl)‐3‐hydroxybutan‐2‐one Derivatives

Author(s) -

Ramazani Ali,

Rouhani Morteza,

Rezaei Aram,

Shajari Nahid,

Souldozi Ali

Publication year - 2011

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.201000219

Subject(s) - chemistry , aryl , butane , organic chemistry , component (thermodynamics) , medicinal chemistry , carboxylic acid , catalysis , alkyl , physics , thermodynamics

Reactions of biacetyl (=butane‐2,3‐dione) with ( N ‐isocyanimino)triphenylphosphorane in the presence of aromatic carboxylic acids proceed smoothly at room temperature and under neutral conditions to afford 3‐(5‐aryl‐1,3,4‐oxadiazol‐2‐yl)‐3‐hydroxybutan‐2‐one derivatives in high yields.

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