Premium
Caragisides A – C, New Isoflavone Glucosides from Caragana conferta with Inhibition of Platelet Aggregation
Author(s) -
Nisar Khan Amna,
Fatima Itrat,
Malik Abdul,
Rasheed Huma
Publication year - 2011
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201000210
Subject(s) - chemistry , caragana , platelet aggregation , two dimensional nuclear magnetic resonance spectroscopy , stereochemistry , botany , platelet , immunology , biology
Abstract Caragisides A–C ( 1 – 3 , resp.), three new isoflavone glucosides, were isolated from the BuOH sub‐fraction of the EtOH extract of the whole plant of Caragana conferta , along with ononoside ( 4 ), reported for the first time from this species. The structures of the new compounds were elucidated by spectroscopic techniques including MS and 2D‐NMR spectroscopy. Compounds 1 – 3 showed significant inhibition of platelet aggregation.