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Double Heck Cross‐Coupling Reactions of Dibrominated Pyridines
Author(s) -
Ali Asad,
Hussain Munawar,
Malik Imran,
Villinger Alexander,
Fischer Christine,
Langer Peter
Publication year - 2010
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.201000108
Subject(s) - chemistry , heck reaction , palladium , coupling reaction , coupling (piping) , organic chemistry , catalysis , polymer chemistry , mechanical engineering , engineering
Double Heck cross‐coupling reactions of 2,3‐ and 3,5‐dibromopyridine with various alkenes afforded the corresponding novel di(alkenyl)pyridines. The Heck reaction of 2,5‐dibromopyridine unexpectedly afforded 5,5′‐di(alkenyl)‐2,2′‐bipyridines by palladium‐catalyzed dimerization to give 5,5′‐dibromo‐2,2′‐bipyridine and subsequent twofold Heck reaction.