Cytotoxic Triterpenoid Saponins Acetylated with Monoterpenoid Acid from  Albizia julibrissin | Zendy

Zou Kun | Zendy; Zhang QingYing | Zendy; Wang Bin | Zendy; Cui JingRong | Zendy; Zhao YuYing | Zendy; Zhang RuYi | Zendy

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Cytotoxic Triterpenoid Saponins Acetylated with Monoterpenoid Acid from Albizia julibrissin

Author(s) -

Zou Kun,

Zhang QingYing,

Wang Bin,

Cui JingRong,

Zhao YuYing,

Zhang RuYi

Publication year - 2010

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.201000059

Subject(s) - chemistry , aglycone , triterpenoid saponin , acetylation , saponin , albizia , oleanane , cancer cell lines , triterpenoid , terpene , terpenoid , stereochemistry , triterpene , glycoside , traditional medicine , biochemistry , cancer cell , cancer , medicine , alternative medicine , pathology , gene

Three new triterpenoid saponins, named julibroside J 16 ( 2 ), julibroside J 17 ( 3 ), and julibroside J 21 ( 4 ), each of which possesses an oleanane triterpenoid aglycone of acacic acid, two monoterpenoid acids, and nine sugar moieties, together with one known saponin, julibroside II ( 1 ), were isolated from the stem bark of Albizia julibrissin by chromatographic methods. Their structures were established by chemical and spectroscopic means. Saponins 1, 2 , and 4 showed inhibitory activities against Bel 7402 human cancer cell line in vitro.

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