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Three New Indole‐Containing Diketopiperazine Alkaloids from a Deep‐Ocean Sediment Derived Fungus Penicillium griseofulvum
Author(s) -
Zhou LiNa,
Zhu TianJiao,
Cai ShengXin,
Gu QianQun,
Li DeHai
Publication year - 2010
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900443
Subject(s) - chemistry , indole test , fungus , marine fungi , dpph , stereochemistry , penicillium , botany , organic chemistry , food science , antioxidant , biology
Three new indole‐containing diketopiperazine alkaloids, named variecolorins M–O ( 1 – 3 ), together with the eight known analogues 4 – 11 , were isolated from a deep‐ocean sediment‐derived fungus, Penicillium griseofulvum. Their structures were determined by analysis of the spectroscopic data. The 2,2‐diphenyl‐1‐picrylhydrazinyl (DPPH) radical‐scavenging activities and the cell‐proliferation inhibitory activities of the three new compounds 1 – 3 were investigated.
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