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Three New Phenylpropanoids from Inula nervosa Wall .
Author(s) -
Yan Lan,
Huang Ying,
Fu JianJun,
Qin JiangJiang,
Zeng Qi,
Zhu Yan,
Yan Shi Kai,
Zhang WeiDong,
Jin HuiZi
Publication year - 2010
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900432
Subject(s) - phenylpropanoid , chemistry , inula , asteraceae , coniferyl alcohol , stereochemistry , traditional medicine , botany , biosynthesis , biochemistry , organic chemistry , lignin , enzyme , traditional chinese medicine , alternative medicine , pathology , biology , medicine
Three new phenylpropanoid compounds, named nervolans A–C ( 1 – 3 , resp.), together with two other known phenylpropanoids, coniferyl diangelate and sinapyl diangelate, were isolated from the aerial parts of Inula nervosa Wall . (Asteraceae), a traditional Chinese medicinal plant. The structures of 1 – 3 were elucidated by detailed spectroscopic analyses, including HR‐ESI‐MS data and 2D‐NMR spectroscopy. Compounds 1 – 5 exhibited mild inhibitory effects against NO production in LPS‐stimulated RAW264.7 cells.