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New Pentacyclic Cucurbitane Glucosides from the Fruits of Citrullus colocynthis Schrad.
Author(s) -
Nayab Durey,
Perveen Shagufta,
Ahmed Zaheer,
Malik Abdul
Publication year - 2010
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900341
Subject(s) - chemistry , citrullus colocynthis , triterpene , dept , two dimensional nuclear magnetic resonance spectroscopy , citrullus , stereochemistry , traditional medicine , botany , medicine , alternative medicine , pathology , biology
Colocynthins A–C ( 1 – 3 , resp.), new pentacyclic cucurbitane type triterpene glucosides, have been isolated from the AcOEt‐soluble fraction of the fruits of Citrullus colocynthis , along with three known compounds, β ‐sitosterol 3‐ O ‐ β ‐ D ‐glucopyranoside, elaterinide, and bryoamaride. Their structures were determined on the basis of 1 H‐ and 13 C‐NMR spectra, DEPT, and COSY, NOESY, HMQC, and HMBC experiments.
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