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Synthesis of Novel Spiropyrimidinones
Author(s) -
Amutha Parasuraman,
Nagarajan Samuthirapandian
Publication year - 2010
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900221
Subject(s) - chemistry , stereochemistry , combinatorial chemistry
Abstract An efficient one‐pot synthesis of new spirocyclic 2‐aminopyrimidinones via the three‐component reaction of a cyclic ketone, alkyl cyanoacetate, and guanidinium carbonate was developed via a domino reaction.