Microwave‐Induced Stereocontrol of  β ‐Lactam Formation with an  N ‐Benzylidene‐9,10‐dihydrophenanthren‐3‐amine  via Staudinger  Cycloaddition | Zendy

Bandyopadhyay Debasish | Zendy; Banik Bimal K. | Zendy

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Microwave‐Induced Stereocontrol of β ‐Lactam Formation with an N ‐Benzylidene‐9,10‐dihydrophenanthren‐3‐amine via Staudinger Cycloaddition

Author(s) -

Bandyopadhyay Debasish,

Banik Bimal K.

Publication year - 2010

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.200900212

Subject(s) - chemistry , cycloaddition , lactam , stereoselectivity , amine gas treating , microwave irradiation , staudinger reaction , stereochemistry , beta lactam , medicinal chemistry , organic chemistry , catalysis , antibiotics , biochemistry

The synthesis of 3‐substituted 4‐phenyl‐1‐(9,10‐dihydrophenanthren‐3‐yl)azetidin‐2‐ones was achieved following Staudinger cycloaddition under microwave‐induced conditions. The stereoselectivity of β ‐lactam formation depended on the power level of the microwave irradiation used in the experiments.

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