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Two New Metabolites, Epoxydine A and B, from Phoma sp.
Author(s) -
Qin Song,
Hussain Hidayat,
Schulz Barbara,
Draeger Siegfried,
Krohn Karsten
Publication year - 2010
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900199
Subject(s) - phoma , chemistry , antifungal , stereochemistry , endophyte , microbiology and biotechnology , botany , biology
The new compounds, epoxydines A and B ( 1 and 2 , resp.), along with the known and related metabolites, 3 – 6 , were isolated from the fungal endophyte Phoma sp. The structures of the new compounds were elucidated by detailed spectroscopic analysis, and the relative configuration of 1 was confirmed by ROESY experiments. Preliminary studies indicated that compounds 2 – 5 possess good antibacterial, antifungal, and algicidal properties. Similarly, compound 1 showed antifungal and algicidal, and compound 6 antibacterial and algicidal properties.