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TiO 2 as a Reusable Catalyst for the One‐Pot Synthesis of 3,4‐Dihydropyrimidin‐2(1 H )‐ones under Solvent‐Free Conditions
Author(s) -
Kassaee Mohammad Zaman,
Masrouri Hassan,
Movahedi Farnaz,
Mohammadi Reza
Publication year - 2010
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900197
Subject(s) - chemistry , catalysis , simplicity , solvent , combinatorial chemistry , reaction conditions , organic chemistry , philosophy , epistemology
An efficient solvent‐free method for the synthesis of various 3,4‐dihydropyrimidin‐2(1 H )‐ones using TiO 2 as a recyclable heterogeneous catalyst is described. Compared to known methods, satisfactory results are obtained with excellent yields, short reaction times, and simplicity in the experimental procedure.