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Verticillane‐Type Diterpenoids and an Eudesmanolide‐Type Sesquiterpene from the Formosan Soft Coral Cespitularia hypotentaculata
Author(s) -
Lin YuChi,
Abd ElRazek Mohamed H.,
Shen YaChing
Publication year - 2010
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900196
Subject(s) - chemistry , sesquiterpene , coral , heteronuclear single quantum coherence spectroscopy , stereochemistry , terpene , moiety , two dimensional nuclear magnetic resonance spectroscopy , art , visual arts
Four new diterpenes, cespihypotins W–Z ( 1 – 4 ), having the verticillane skeleton and characterized by an α , β ‐unsaturated γ ‐hydroxycyclopentanone moiety, and a new eudesmanolide‐type sesquiterpene, cespilactam A ( 5 ), containing an α , β ‐unsaturated γ ‐lactam residue, were isolated from the AcOEt‐soluble fraction of the Taiwanese soft coral Cespitularia hypotentaculata. The structure and relative configuration of these metabolites was elucidated through extensive interpretation of MS, COSY, HSQC, HMBC, and NOESY experiments and by comparison of their NMR data with those of related compounds.