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Catunaregin and Epicatunaregin, Two Norneolignans Possessing an Unprecedented Skeleton from Catunaregam spinosa
Author(s) -
Gao GuangChun,
Luo XiongMing,
Wei XiaoYi,
Qi ShuHua,
Yin Hao,
Xiao ZhiHui,
Zhang Si
Publication year - 2010
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900193
Subject(s) - chemistry , stereochemistry , bark (sound) , cancer cell lines , ring (chemistry) , skeleton (computer programming) , mangrove , two dimensional nuclear magnetic resonance spectroscopy , organic chemistry , cancer cell , cancer , medicine , ecology , physics , acoustics , biology , computer science , programming language
Catunaregin ( 1 ) and epicatunaregin ( 2 ), two novel norneolignans with a unique O‐bridged furopyran ring, together with three known neolignans, ficusal, balanophonin, and 5″‐methoxy‐4″‐ O ‐(8‐guaiacylglycerol)buddlenol A, were isolated from the stem bark of Catunaregam spinosa , a Chinese mangrove associate. Their structures were elucidated by spectroscopic means, including two‐dimensional NMR techniques. Compounds 1 and 2 exhibited moderate inhibition against the mammary cancer F10 cell line.